Intention-to-treat analysis (ITT)
In Trial design & structure
Intention-to-treat analysis includes every randomized participant in the group they were assigned to, regardless of what treatment they actually received or whether they completed the trial. It preserves the balance that randomization created and gives a realistic picture of the treatment in practice. It is normally the primary analysis in a confirmatory trial.
Example
A participant randomized to the active arm stops taking the drug after one week. In an intention-to-treat analysis their data still counts in the active arm.
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